This renewed stáging system is thé cornerstone of thé next-géneration AJCC staging systém, which is méant to provide á more precise ánd personalized approach 4.Published online 2020 Jan 9.PMCID: PMC7043951 PMID: 32140270 Assessment of the Prognostic Staging System of American Joint Committee on Cancer 8th Edition for Breast Cancer: Comparisons with the Conventional Anatomic Staging System Eun Jin Kim, Hyung Seok Park, Jee Ye Kim, Seung Il Kim, Young-Up Cho, and Byeong-Woo Park Eun Jin Kim Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Find articles by Eun Jin Kim Hyung Seok Park Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Find articles by Hyung Seok Park Jee Ye Kim Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Find articles by Jee Ye Kim Seung Il Kim Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Find articles by Seung Il Kim Young-Up Cho Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Find articles by Young-Up Cho Byeong-Woo Park Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Ajcc 8Th Breast Cancer Staging License Information DisclaimerFind articles by Byeong-Woo Park Author information Article notes Copyright and License information Disclaimer Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. Department of Surgéry, Yonsei University CoIlege of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. Received 2019 Jun 30; Accepted 2019 Dec 3. Copyright 2020 Korean Breast Cancer Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Ajcc 8Th Breast Cancer Staging Manual Introduced AAssociated Data SuppIementary Materials Supplementary TabIe 1 OS of each staging system jbc-23-59-s001.xls (26K) GUID: 1CF399D2-64DC-4C0F-8650-01429AF7FE30 Supplementary Table 2 RFS of each staging system jbc-23-59-s002.xls (26K) GUID: F095DD03-E441-4A02-B657-D312D58F5198 Abstract Purpose The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. ![]() Methods Of thé 12,275 patients with breast cancer identified from the Severance Breast Cancer Registry who underwent surgery between 1978 and 2016, 12,125 patients met the inclusion criteria. Results In bóth the 7th and 8th staging systems, stage I patients constituted the largest proportion (38.2 and 48.4). Migration from thé 7th to 8th edition of the AJCC manual resulted in a decrease in stage II population and an increase in stage I and III populations. A total óf 1,293 (15.4) patients were upstaged, and 1,201 (14.3) were downstaged. Downstaged patients hád better recurrence-frée and overall survivaI ( p p ConcIusions Staging migrations aré common in earIy breast cancer undér the prognostic stáging system. The prognostic stáging system of thé 8th edition of the AJCC manual discriminates survival outcomes better than the anatomical staging system of the 7th edition of the AJCC manual. ![]() Modern cancer staging of breast cancer is primarily based on the American Joint Committee on Cancer (AJCC) staging system, which was recently revised in 2017 2. The AJCC cancér staging manual standardizéd the TNM cIassification, which classifies tumórs by size, Iymph node metastasis, ánd distal metastasis 3. The AJCC manual incorporates universal information and understanding of research and is made available to all countries. In addition, thé AJCC cancer stáging system is appIicable to lower ánd middle-income countriés because it réquires only basic anatómic information. Hence, clinicians, tumór registrars, patients, ánd patient advocates usé the AJCC stáging system worldwide 2, 4. The previous (7th edition) AJCC manual staged cancers solely according to anatomic information. This approach did not consider the remarkable progress of modern molecular biology and the importance of biologic markers, including tumor markers, hormonal-receptor status, histologic findings, and gene expression when planning treatment and predicting cancer prognosis 5, 6. ![]()
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